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The exact mechanism by which hesperidin reduced the iron induced oxidative stress is not clearly known

Krperlicher und seelischer Stress, unausgewogene Ernhrung, Schlafprobleme und zu wenig Schlaf sowie Alkohol- und Zigarettenkonsum knnen dazu fhren, dass der Krper mehr Glutathion verbraucht, als er selbst herstellen und recyceln kann

Stable over-expression of the 2-oxoglutarate carrier enhances neuronal cell resistance to oxidative stress via Bcl-2-dependent mitochondrial GSH transport